6-MP 50 mg (Mercaptopurine)
6-MP 50 mg contains mercaptopurine, a purine antagonist used in the maintenance treatment of Acute Lymphoblastic Leukemia (ALL). It interferes with DNA and RNA synthesis to suppress abnormal white blood cell growth.
Product Introduction
Mercaptopurine is a thiopurine antimetabolite that inhibits purine synthesis and slows the growth of rapidly dividing leukemic cells. It is commonly used during the maintenance phase of ALL therapy, often alongside methotrexate.
Uses of 6-MP 50 mg
- Acute Lymphoblastic Leukemia (ALL) – maintenance therapy
- Acute Myeloid Leukemia (selected protocols)
- Chronic Myelogenous Leukemia (rare or older protocols)
- Specialist-directed autoimmune use (rare)
Note: Use only within an approved oncology protocol.
Benefits
- Helps maintain long-term remission in ALL
- Oral tablet suitable for home administration
- Well-established in leukemia treatment regimens
- Dosing can be adjusted based on genetic testing
In Treatment of Worm Infections
Important: Mercaptopurine does not treat parasitic infections. This section exists only to preserve platform structure.
Side Effects
Common side effects
- Nausea and vomiting
- Loss of appetite
- Fatigue
- Diarrhoea
- Skin rash
Bone marrow suppression, infections, liver toxicity, pancreatitis, and mouth ulcers. Seek immediate medical attention for fever, bleeding, jaundice, or severe abdominal pain.
How to Use
- Take exactly as prescribed by your oncologist
- Usually taken once daily
- Take on an empty stomach if advised
- Avoid milk or dairy within 2 hours
- Do not alter the dose without medical advice
- Regular blood tests are required
How It Works
Mercaptopurine converts into active thioguanine nucleotides that disrupt DNA and RNA synthesis, preventing leukemic cell proliferation and supporting remission maintenance.
Safety Advice
| Pregnancy | Not recommended; contraception required |
| Breastfeeding | Avoid during therapy |
| Liver disease | Use with caution and monitoring |
| Alcohol | Avoid due to liver risk |
| Vaccines | Avoid live vaccines |
| Drug interactions | Allopurinol, febuxostat, warfarin |
Fact Box
| Generic name | Mercaptopurine |
| Brand | 6-MP 50 mg |
| Drug class | Thiopurine antimetabolite |
| Form | Oral tablet |
| Use | ALL maintenance therapy |
| Prescription | Required |
